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Acne treatment london - Acne
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The Acne Research Library brings you the latest research
on Acne Treatments fully referenced research
papers, clinical studies, articles and products to help
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Topical Liposomal Gel Of Tretinoin For The Treatment Of Acne
By A J Jackson
Summary of research:
An attempt was made to pharmaceutically develop a topical liposomal tretinoin ( TRE ) gel and clinically evaluate the developed formulation for the treatment of in patients. Liposomes of TRE were prepared using the lipid film hydration technique and the entrapment efficiency of TRE in liposomes was optimized to 79. 96 %. The drug retention in liposomes and in liposomal TRE gel ( Carbopol 934 gel base ) studied at three storage conditions indicated maximum drug retention at refrigeration temperature. For liposomal TRE gel, reduced drug leakage was observed as compared to that of liposomes at all three storage conditions. Diffusion studies of plain TRE gel and liposomal TRE gel suggested perpetuation ( 3. 4 times reduction in flux value ) of drug diffusion and halfway two - fold increase in
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skin drug retention after liposomal encapsulation of drug. A comparative double - blind clinical study of the developed liposomal TRE gel, carried out on 30 patients over a period of 3 months, demonstrated significant enhancement ( about 1. 5 - fold ) in drug efficacy. More remarkable improvement was observed in the treatment of comedones, where the mean percent reduction in lesions increased from 62. 36 % for plain TRE gel to 94. 17 % for liposomal TRE gel. Erythema and cat fit associated with the use of casual TRE gel was reduced absolutely with the use of liposomal TRE gel. The findings of this investigation therefore underscore potential utility of commercialization of liposomal TRE gel in the treatment of Acne.
Report Title: Topical liposomal gel of tretinoin for the treatment of Acne: research and clinical implications.
Researcher ( s ): Patel VB, Misra A, Marfatia YS
From Journal: Pharm Dev Technol, 5 ( 4 ): 455 - 64 2000
To earn the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Matching medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a reserved interest in skin care.
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We scour the international medical databases to obtain only reliable,
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Obesity tied to risk of psychiatric disorders
NEW YORK (Reuters Health) - Obesity is a well known risk factor for certain physical health problems, but a new study suggests that heavy adults also have higher rates of psychiatric disorders.Ankle sprains cause lasting problems for some
NEW YORK (Reuters Health) - While many people who sprain an ankle get back on their feet quickly, some continue to have pain and other problems for months to years, a new study shows.Chinese club moss may help Alzheimer's
NEW YORK (Reuters Health) - An extract from Chinese club moss shows promise as a treatment for people with Alzheimer's disease, researchers report after analyzing combined data from multiple trials conducted in China.Popcorn fans eat more whole grain: study
NEW YORK (Reuters Health) - People who snack on popcorn may consume more whole grains and less meat than their peers who don't, new research shows.Cancer drug sales could hit $80 billion by 2011: IMS
NEW YORK (Reuters) - Sales of cancer drugs will grow at nearly double the rate of the global pharmaceutical market and could reach $80 billion by 2012, according to IMS Health, which tracks prescription drug sales.Too much alcohol damages heart and arteries
CHICAGO (Reuters) - Heavy drinking causes high blood pressure, stiff arteries and rigid heart muscles in men and enlarged hearts in women, boosting their risk of having heart attacks and strokes, researchers said on Wednesday.U.S. recommends shingles vaccine for age 60 and up
WASHINGTON (Reuters) - The U.S. Centers for Disease Control and Prevention on Thursday recommended that people aged 60 and older should get Merck & Co Inc's vaccine Zostavax to protect against shingles.Nerve block cuts hot flashes after breast cancer
NEW YORK (Reuters Health) - Blocking parts of the nervous system that regulate body temperature can reduce hot flashes and improve sleep in survivors of breast cancer, researchers reported on Thursday.
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Essential Fatty Acids And Acne
By A J Jackson
Summary of research: Acne is characterized by hyperkeratosis of the follicular epithelium, leading to horny impactions that may lie dormant as open or closed comedones or can Read more...
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Treating Acne Vulgaris With Antiandrogens2
By A J Jackson
Summary of research: The results of hormonal antiandrogen therapy obtained in our group of 12 patients suffering from Acne premenstrualis are reported. The patients with the Read more...
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