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An inflammatory skin disease that affects the tiny pores that cover the face, arms, back and chest as well as the oil glands attached to them.
   

 


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Vitamin E Does Not Reduce The Side - effects Of Isotretinoin In The Treatment Of Acne Vulgaris
By A J Jackson


Summary of research:

Isotretinoin is widely used in the treatment of severe, recalcitrant, nodular Acne. Mucocutaneous side - effects are seen in the great majority of patients and some of them have elevations in their serum lipid and liver enzyme profiles. Recently, it has been shown that addition of vitamin E decreased the toxicity of high - dose retinoids. OBJECTIVE: The purpose of this investigator - blinded, randomized study was to assess whether vitamin E would reduce the side - effects of isotretinoin in the treatment of vulgaris.

The researchers methods: Eighty two patients were randomly assigned to one of two treatment groups with isotretinoin ( 1 mg / kg / day ) alone



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or combined with vitamin E ( 800 IU / day ). The treatment duration was 16 weeks. Mucocutaneous side - effects such as facial erythema, facial dryness, cheilitis and serum lipid and liver enzyme profiles were assessed.

The outcome of this Research: There was no difference in the incidence and severity of side - effects related to isotretinoin between the two treatment groups.

The report's conclusion: Eight hundred IU / day vitamin E did not improve the side - effects of 1 mg / kg / day of isotretinoin in the treatment of vulgaris.

Report Title: Vitamin E does not reduce the side - effects of isotretinoin in the treatment of vulgaris.
Researcher ( s ): Kus S, Gün D, Demirçay Z, Sur H
From Journal: Int J Dermatol, 44 ( 3 ): 248 - 51 2005

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

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We scour the international medical databases to obtain only reliable, fully referenced articles & research papers on Acne Treatments.

If there is a specific topic related to Acne Treatments that you would like us to cover, please feel free to contact us at any time.

The Prevalence Of Acne On The Basis Of Physical Examination
By A J Jackson
Summary of survey: It has been suggested that cystic Acne is rare in women 15 to 44 years of age and infrequent in men. OBJECTIVE: To determine the prevalence of Acne, we Read more...

Topical Liposomal Gel Of Tretinoin For The Treatment Of Acne
By A J Jackson
Summary of research: An attempt was made to pharmaceutically develop a topical liposomal tretinoin ( TRE ) gel and clinically evaluate the developed formulation for the Read more...


 
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Advances In The Topical Treatment Of Acne And Rosacea
By A J Jackson
Summary of research: Acne and rosacea are common skin diseases which may present similarly and both involve inflammation. Both can result in significant cosmetic impairment and Read more...








Acne Treatment With Oral Zinc And Vitamin A
By A J Jackson
Summary of research: The serum levels of zinc, vitamin A and retinol binding protein ( RBP ) were studied in 75 Acne patients before and during oral treatment with zinc, Read more...
High School Dietary Dairy Intake And Teenage Acne
By A J Jackson
Summary of tour: Previous studies suggest possible associations between The researchersstern diet and Acne. The researchers quizzed info from the Nurses Health Study II to Read more...
The Problem Of Vitamin B6 - b12 Acne Therapy
By A J Jackson
Summary of research: Deterioration of Acne vulgaris or eruption of an Acneiform exanthema could be established during treatment with vitamin B6 and / or vitamin B12 in 14 Read more...

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