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a chronic disorder of the hair follicles and sebaceous glands. Acne is characterized by black heads, pimple outbreaks, cysts, infected abscesses, and (sometimes) scarring.
   

 


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Vitamin E Does Not Reduce The Side - effects Of Isotretinoin In The Treatment Of Acne Vulgaris
By A J Jackson


Summary of research:

Isotretinoin is widely used in the treatment of severe, recalcitrant, nodular Acne. Mucocutaneous side - effects are seen in the great majority of patients and some of them have elevations in their serum lipid and liver enzyme profiles. Recently, it has been shown that addition of vitamin E decreased the toxicity of high - dose retinoids. OBJECTIVE: The purpose of this investigator - blinded, randomized study was to assess whether vitamin E would reduce the side - effects of isotretinoin in the treatment of vulgaris.

The researchers methods: Eighty two patients were randomly assigned to one of two treatment groups with isotretinoin ( 1 mg / kg / day ) alone



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or combined with vitamin E ( 800 IU / day ). The treatment duration was 16 weeks. Mucocutaneous side - effects such as facial erythema, facial dryness, cheilitis and serum lipid and liver enzyme profiles were assessed.

The outcome of this Research: There was no difference in the incidence and severity of side - effects related to isotretinoin between the two treatment groups.

The report's conclusion: Eight hundred IU / day vitamin E did not improve the side - effects of 1 mg / kg / day of isotretinoin in the treatment of vulgaris.

Report Title: Vitamin E does not reduce the side - effects of isotretinoin in the treatment of vulgaris.
Researcher ( s ): Kus S, Gün D, Demirçay Z, Sur H
From Journal: Int J Dermatol, 44 ( 3 ): 248 - 51 2005

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

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We scour the international medical databases to obtain only reliable, fully referenced articles & research papers on Acne Treatments.

If there is a specific topic related to Acne Treatments that you would like us to cover, please feel free to contact us at any time.

Laser Therapy Of Acne Vulgaris
By A J Jackson
Summary of research: BACKGROUND AND OBJECTIVES: The booked - infrared ( NIR ) laser radiation well-timed to its high penetration depth is widely used in phototherapy. In Read more...

New Age Of Acne Therapy - Light Treatment
By A J Jackson
Summary of research: Current treatments for Acne vulgaris include topical and oral medications that counteract microcomedone formation, sebum production, Propionibacterium Read more...


 
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Overview Of The Evaluation And Management Of Acne Vulgaris
By A J Jackson
Summary of research: Acne vulgaris is a disease of the pilosebaceous unit where abnormally adherent keratinocytes cause plugging of the follicular duct followed by accumulation Read more...








Concomitant Administration Of Vitamin E Does Not Change The Side Effects Of Isotretinoin As Used In Acne Vulgaris
By A J Jackson
Summary of research: Isotretinoin treatment is frequently associated with reversible, dose - related side effects. Recent studies claimed that combining vitamin E with high - Read more...
Beliefs And Perception Of Youth Toward Acne Vulgaris
By A J Jackson
Summary of research: OBJECTIVE: This study was carried out to assess the knowledge, concepts and perceptions of the youth towards Acne. The researchers methods: Read more...
Evaluation Of Pulsed Light And Radiofrequency Combined For The Treatment Of Acne Vulgaris
By A J Jackson
Summary of inquire into: Light and radiofrequency ( RF ) devices have recently been used to treat Acne in selected patients. OBJECTIVE: To investigate the safety and efficacy Read more...

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