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Acne causes - Acne
Treatments
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The Acne Research Library brings you the latest research
on Acne Treatments fully referenced research
papers, clinical studies, articles and products to help
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Effectiveness Of Photodynamic Therapy For Acne
By A J Jackson
Summary of research:
Photodynamic therapy ( PDT ) involves the activation of a photosensitizing agent by light to produce oxygen intermediates that destroy target tissues. Topical 5 - aminolevulinic acid ( ALA ) is converted to protoporphyrin IX, a very potent photosensitizer, which accumulates in human skin, particularly in the epidermis and its appendages. Objective: To study the effect of PDT in vulgaris using topical ALA and intense pulsed light ( IPL ).
The researchers methods: Thirteen individuals with varied degrees of were treated hard by a 3 - moment washout period. Twenty percent ALA hydrochloride ( DUSA Pharmaceuticals, Wilmington, MA, USA ) was applied to half of the face, and after 3 hours, the full face was exposed to intense pulsed light ( Quantum SR, Lumenis, Santa Clara, CA, USA ) using a 560 nm cutoff filter starting at a fluence of 26 J / cm. The procedure was done twice at 2 - week intervals, and the patients were clinically evaluated on the
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second, fourth, and eighth weeks.
The the nod of this Research: All patients had no apparent improvement on the second year on both facial halves. In fact, some of the patients developed acute Acneiform eruptions on the side treated with ALA. By the fourth week, however, most of the patients had visible improvement of facial that was more significant on the ALA - treated side of the face. This persisted until the eighth epoch operation - treatment. On the other assist, the facial half treated with intense pulsed light only showed a return to baseline of their facial Acne.
The report's conclusions: ALA - IPL are favorable in the management of vulgaris and may be used in combination with other forms of treatment or may embody an alternative treatment for patients who produce not thirst to take systemic retinoids.
Report Interval: Effectiveness of photodynamic therapy with topical 5 - aminolevulinic acid and intense pulsed light versus intense pulsed light alone in the treatment of vulgaris: comparative study.
Researcher ( s ): Santos MA, Belo VG, Santos G
From Logbook: Dermatol Surg, 31 ( 8 Pt 1 ): 910 - 5 2005
To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated thing 27 languages. He has a special interest in skin care.
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