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Effect Of Zinc Gluconate On Propionibacterium Acnes
By A J Jackson


Summary of research:

Tetracyclines and macrolide antibiotics have been in use for treatment for more than 20 years. Since 1992 increasing resistance to these antibiotics, and especially to erythromycin, is reported with Propionibacterium Acnes. Zinc salts have demonstrated their efficacy in inflammatory treatment as well as their bacteriostatic hustle against Propionibacterium Acnes. The objective of our work was firstly to halt whether the clinical con - inflammatory efficacy of zinc salts was altered in the presence of erythromycin resistant strains in vivo, and secondly to study the in vitro and in vivo end product of zinc on the sensitivity of Propionibacterium Acnes strains to erythromycin. Thirty patients with inflammatory were treated by zinc gluconate with a daily dose of 30

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mg for two months and bacteriologic samples were taken at D0, D30 and D60. In vivo, this study displayed a diminution in the character of inflammatory lesions after a 2 - month treatment whether or not Propionibacterium Acnes traipse was present. Concurrently, in vitro appendage of zinc salts in the culture media of Propionibacterium Acnes reduced resistance of Propionibacterium Acnes strains to erythromycin. Thus, association of zinc salts via a systemic route and topical erythromycin treatment seems an interesting option in the light of an increasing number of patients carrying erythromycin resistant Propionibacterium Acnes strains.
Report Duration: Effect of zinc gluconate on propionibacterium Acnes resistance to erythromycin in patients with inflammatory Acne: in vitro and in vivo study.
Researcher ( s ): Dreno B, Foulc P, Reynaud A, Moyse D, Habert H, Richet H
From Magazine: Eur J Dermatol, 15 ( 3 ): 152 - 5 2005

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Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a old columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which posses been published around the world & translated into 27 languages. He has a proper interest in skin care.

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