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Skin disorder caused by inflammation of the skin glands and hair follicles found primarily in adolescents and marked by pimples, especially on the face.

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Long - term Safety Of Spironolactone In Acne
By A J Jackson

Summary of research:

Spironolactone has been used for over 20 years as an antiandrogen in the treatment of and hirsutism. No long - term studies of the safety of spironolactone used in this manner own been published. The researchers present a study of the long - term safety and tolerance of spironolactone in 91 women with who were followed for up to 8 years.

The researchers methods: A survey questionnaire was sent to 210 patients, and a comparison doodle review of all patients to whom the inquire into was sent was made.

The outcome of this Research: Ninety - one completed surveys were analyzed, comprising 506 person - years of followup and 200 person - years of spironolactone exposure. Tight-fisted treatment skein was 28. 5 months ( span

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= 0. 5 - 122 months ). During the 8 - year followup period, crack were no cases of serious indisposition attributable to spironolactone use. Side effects were present in 59 % and resulted in cessation of the drug in 15 %. Diuretic effect and menstrual irregularities were the supremely common adverse effects.

The Report's Conclusions: After 200 person - years of exposure to spironolactone and 506 person - years of followup being 8 years, no serious illnesses thought to be attributed to spironolactone were reported. The long - term use of spironolactone in the treatment of in women appears to be safe. Side effects, however, are common, although not usually a cause for stopping the drug.
Report Duration: Long - term safety of spironolactone in Acne: results of an 8 - year followup study.
Researcher ( s ): Shaw JC, White LE
From Journal: J Cutan Med Surg, 6 ( 6 ): 541 - 5 2002

To obtain the humungous report, please visitPurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which retain been published around the world & translated into 27 languages. He has a special bag in skin care.

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