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Essential Fatty Acids And Acne
By A J Jackson

Summary of research:

Acne is characterized by hyperkeratosis of the follicular epithelium, leading to horny impactions that may lie dormant as open or closed comedones or can cause inflammation of the follicle. Although persons with have consistently been observed to have elevated levels of sebum secretion, no mechanism relating sebum secretion rates to comedogenesis is known. patients have also been shown to have low levels of linoleic acid in their skin surface lipids.

To explain this observation, the hypothesis is advanced that the linoleate concentration in human sebum depends on the quantity of linoleic acid present in each sebaceous cell

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at the commencement of its differentiation and on the extent to which this initial charge is diluted by subsequent endogenous lipid synthesis in each sebaceous cell. A corollary hypothesis holds that low concentrations of linoleate in sebum impose a state of essential fatty acid deficiency on the cells of the follicular epithelium and induce the characteristic response of hyperkeratosis. Both hypotheses could hold, without there being a systemic deficiency of linoleic acid, simply as the result of elevated lipogenesis in individual sebaceous cells.

Report Title: Essential fatty acids and Acne.
Researcher ( s ): Downing DT, Stewart ME, The researchersrtz PW, Strauss JS
From Journal: J Am Acad Dermatol, 14 ( 2 Pt 1 ): 221 - 5 1986

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

We scour the international medical databases to obtain only reliable, fully referenced articles & research papers on Acne Treatments.

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