Acne spots - Acne Treatments

Efficacy And Safety Of Stabilised Hydrogen Peroxide Cream For Acne
By A J Jackson


Summary of research:

Benzoyl peroxide ( BP ) is a first - line topical treatment in vulgaris ( AV ). However, its use can cause mild skin irritation and dryness. A new formulation of hydrogen peroxide stabilised ( HPS ) in monoglycerides cream ( Crystacide 1 % ), indicated in the topical treatment of superficial skin infections, is now available as an alternative treatment. STUDY AIM: To evaluate efficacy and local tolerability of HPS in mild - to - moderate AV in comparison with BP gel. METHODS AND PATIENTS: In a randomised, prospective, investigator - masked parallel - group, 8 - present trial, 60 patients ( 24 men, 36 women, mean age 25 + / - 6 years ) with mild - to - moderate AV, affecting mainly the face, were enrolled in the study, after their informed pass on. HPS or BP ( PanOxyl gel 4 % ) was applied topically twice daily for 8 weeks. STUDY OUTCOMES: The study endpoints were: ( 1 ) Decrease in mean inflammatory ( IL ), noninflammatory ( NIL ) and total ( TL ) Acneic lesions in comparison with baseline; ( 2 ) Local tolerability assessed evaluating erythema, dryness and burning sensation, using a 0 - 3 qualitative score ( score 0 = flat broke tolerability; see through 3 = very good tolerability ).

The adjustment of this Research: TL, NIL, and IL were assessed by an investigator

Home Acne Laser Devices

Kids' tummy bugs tied to irritable bowels
NEW YORK (Reuters Health) - A serious bout with a stomach bug can raise a child's risk of having irritable bowel syndrome (IBS) later on, new research shows.
Vaginal birth after cesarean underused: panel
NEW YORK (Reuters Health) - If you're pregnant and have had a cesarean section before, chances are you'll have one again. In at least one-third of US hospitals, a repeat cesarean is the only option, and nine in 10 women end up getting one -- a fact that had experts worried at a national conference this week on vaginal birth after cesarean, or VBAC.
Music class may benefit kids with cochlear implants
NEW YORK (Reuters Health) - Music class may help improve certain types of sound perception in deaf children who have cochlear implants, a new study hints.
More cocaine-overdose deaths seen on hotter days
NEW YORK (Reuters Health) - The number of New Yorkers who die of cocaine overdose appears to go up when the temperature surpasses 75 degrees, a new study suggests.
Smoking years key factor in lower Parkinson's risk
NEW YORK (Reuters Health) - Several studies have shown that smokers have a lower risk of developing Parkinson's disease. A new study shows that it's how many years of smoking a person has under their belt -- rather than how much they smoke every day -- that matters.
Pelosi faces biggest test on U.S. healthcare vote
*House speaker needs 216 votes to pass final bill
Live kidney donors do not die sooner: study
CHICAGO (Reuters) - Healthy Americans who donated a kidney were not at higher risk of dying afterward, which may reassure potential donors and help shorten the long waiting list for an organ, U.S. researchers said on Tuesday.
Study says fat is the sixth "taste"
SYDNEY (Reuters Life!) - People sensitive to the taste of fat tend to eat less of it and are less likely to be overweight, according to Australian research that found human tongues can detect fatty tastes.

innocent of treatment allocation at baseline, and week 8. The tolerability score ( TS ) was assessed at week 4 and 8. At baseline, the two groups were well matched for the main clinical and demographic characteristics. All patients concluded the trial. At week 0, in the HPS cluster TL, NIL and IL ( mean + / - SD ) were: 35 + / - 8, 20 + / - 6 and 16 + / - 7. At week 8, HPS reduced TL to 16 + / - 7; Aught to 9 + / - 3 and IL to 7 + / - 3 ( p < 0. 001 ). At baseline, TL, NIL and IL, in the BP group, were 32 + / - 9, 24 + / - 8 and 18 + / - 7, respectively. At week 8, BP truly needy TL, NIL and IL to 14 + / - 9; 7 + / - 5 and 7 + / - 3 ( p < 0. 001 ). In comparison with baseline values, the percentage reductions of IL were 58 % and 61 % for HPS and BP, respectively ( p = n. s. ). At the end of the study the TS was 2. 9 + / - 0. 2 in HPS group and 2. 4 + / - 0. 8 in BP group ( p < 0. 025 ). Two patients in HPS group ( 6 % ) and seven patients ( 23 % ) in BP group suffered from mild - to - moderate local erythema.

The Report's Conclusions: HPS has shown to be as effective as BP in reducing both inflammatory and noninflammatory AV lesions in patients with mild - to - moderate disease. In comparison with BP 4 % gel, HPS cream shows a better local tolerability profile.

Report Title: Efficacy and safety of stabilised hydrogen peroxide cream ( Crystacide ) in mild - to - moderate vulgaris: a randomised, controlled trial versus benzoyl peroxide gel.
Researcher ( s ): Milani M, Bigardi A, Zavattarelli M
From Journal: Curr Med Res Opin, 19 ( 2 ): 135 - 8 2003

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the sphere & translated into 27 languages. He has a special interest in skin care.

	Enter your search terms Submit search form
	Web www.acneresearchlibrary.com