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Acne is an inflammatory disease of the skin, caused by changes in the pilosebaseous units (skin structures consisting of a hair follicle and its associated sebaceous gland). The most common form of Acne is known as "Acne vulgaris", which means common Acne. Excessive secretion of oils from the glands combine with naturally occurring dead skin cells to block the hair follicles. ...

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Japanese Herbal Medicine Treatment For Acne
By A J Jackson

Summary of research:

On the basis of recent reports that keigai - rengyo - to ( TJ - 50 ), an oral Japanese Kampo ( herb ) medicine, is clinically effective in treating Acne, and that tetracyclines are effective against by acting directly as an antioxidant on infiltrated neutrophils, we investigated the effect of TJ - 50 on the generation of reactive oxygen species ( ROS ), using human neutrophils and a cell - free, xanthine - xanthine oxidase system. The species investigated were superoxide radical anion ( O2 - ), hydrogen peroxide ( H2O2 ), and hydroxyl radical ( OH. ). In addition, neutrophil chemotaxis, phagocytosis and calcium concentration, [Ca2 + ]i in neutrophils were also

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assessed. TJ - 50 significantly decreased neutrophil - generated O2 -, H2O2 and OH. in a dose - dependent manner. Three kinds of ROS generated in the cell - free system were also reduced in the presence of TJ - 50. On the other hand, the medicine did not markedly affect neutrophil chemotaxis, phagocytosis or [Ca2 + ]i in neutrophils. The researchers' results indicate that the clinical effectiveness of TJ - 50 in the treatment of may be due partly to its antioxidant action on infiltrated neutrophils.

Report Title: Effect of keigai - rengyo - to, a Japanese kampo medicine, on neutrophil functions: a possible mechanism of action of keigai - rengyo - to in Acne.
Researcher ( s ): Akamatsu H, Asada Y, Horio T
From Journal: J Int Med Res, 25 ( 5 ): 255 - 65 1997

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

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	Milk Consumption And Acne In Adolescent Girls By A J Jackson Summary of research: There has been a peculiar paucity of evidence for an association between diet and Acne. The researchers' previous studies pique that there is an Read more...
	Using Hypnosis To Facilitate Resolution Of Psychogenic Excoriations In Acne By A J Jackson Summary of research: Hypnotic suggestion successfully alleviated the behavioral picking aspect of Acne excoriée des juenes filles in a pregnant woman who had been picking at Read more...

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Summary of research: Acne is one of the most common dermatological diseases, affecting about 50 % of adolescents. Different chemical peelings are used in local treatment, Read more...

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