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Intense Pulsed Light - Acne Treatment
By A J Jackson


Summary of research:

BACKGROUND AND OBJECTIVES: The going to intense pulsed light ( IPL ) on Asian skin often differs from that on Caucasian skin. The study reported herein evaluated the effect on vulgaris of IPL alone and when IPL was combined with photodynamic therapy ( PDT ) using topical methyl aminolevulinate ( MAL ) in Asians. STUDY DESIGN / MATERIALS AND

The researchers methods: Thirty Chinese subjects with phototypes IV or V and moderate were enrolled for a randomized, half - facial treatment study with IPL alone, IPL with PDT, or as controls. Sixteen percent MAL cream was convenient to half of the face 30 minutes before treatment in the PDT group. The IPL was provided by the Ellipse Flex profile ( Danish Dermatologic Development, Denmark ), which emitted wavelengths of 530 to 750 nm. The subjects were treated four times at 3 - week intervals. Single passes of double pulses with a 10 milliseconds delay and a pulse duration of 2. 5 milliseconds were used. The opinion of inflammatory and non - inflammatory lesions by two blinded investigators was based on standardized photographs that were taken before each treatment, and at 4 and 12 weeks after the final treatment.

The outcome of this Research: Twenty - three patients completed the study. The mean reduction of the inflammatory lesion comprehend was 53 % in the PDT group, 22 % in the IPL group, and 72 % in the government grade at 4 weeks, and 65 % in the PDT group, 23 % in the IPL group, and 88 % in control

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lot at 12 weeks. The mean clearance of non - inflammatory lesions was 52 % in the PDT group, 15 % in the IPL accumulation, and 14 % in the regulation group at 4 weeks, and 38 % in the PDT group and 44 % in the IPL group at 12 weeks, when and an increase of 15 % was noted in the control group. Most patients experienced a reduction of inflammatory lesions that was not statistically significant on the PDT - treated side ( P = 0. 06 ) or the IPL - treated side ( P = 0. 82 ) at 12 weeks after treatment. Pretreatment with MAL resulted in a better clearance of inflammatory than IPL express. There were no statistically significant differences between the intervention groups and the control group in the mean reduction of inflammatory lesions. Powerful reductions of non - inflammatory lesions were pragmatic in the MAL - PDT group ( 38 %, P = 0. 05 ) and IPL groups ( 43 %, P = 0. 00 ) 12 weeks after treatment. Twenty - five percent of the subjects in the PDT group withdrew because of intolerance to procedure - related repentance.

The Report's Conclusions: MAL - PDT using IPL and MAL in Asians did not lead to significant improvement of moderate inflammatory compared with the control group. However, there was a delayed effect on non - inflammatory lesions, with significant reductions in both the PDT and IPL groups. A proportion of patients could not sympathize the discomfort that was related to PDT despite the short MAL incubation.

Report Title: A comparative study of intense pulsed light alone and its combination with photodynamic therapy for the treatment of facial in Asian skin.
Researcher ( s ): Yeung CK, Shek SY, Bjerring P, Yu CS, Kono T, Chan HH
From Journal: Lasers Surg Med, 39 ( 1 ): 1 - 6 2007

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Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

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