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Laser Therapy Of Acne Vulgaris
By A J Jackson
Summary of research:
BACKGROUND AND OBJECTIVES: The booked - infrared ( NIR ) laser radiation well-timed to its high penetration depth is widely used in phototherapy. In application to skin appendages, a high selectivity of laser treatment is needed to prevent light life on surrounding tissues. Indocyanine pliable ( ICG ) dye may provide a high selectivity of treatment due to effective ICG uploading by a target and its narrow band of considerable absorption just at the wavelength of the NIR diode laser. The destination of this study is to demonstrate the efficacy of the NIR diode laser phototherapy in combination with topical application of ICG suggested for amiable and scorching treatment of vulgaris. STUDY DESIGN / MATERIALS AND
The researchers methods: Twenty - two volunteers with facile or back - located were enrolled. Skin sites of subjects were stained by ICG and irradiated by NIR laser - diode light ( 803 or 809 nm ). One mg / ml solution of ICG was pragmatic for 5 or 15 minutes to the cleaned skin site. Untreated, only stained and only light fulgent skin areas served as controls. For soft treatment, the low - intensity ( 803 nm, 10 - 50 mW / cm ( 2 ), 5 - 10 minutes ) or the medium - intensity ( 809 nm, 150 - 190 mW / cm ( 2 ), 15 minutes
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) protocols were used. The single and multiple ( up to 8 - 9 ) treatments were provided. The individual lesions were photothermally treated at 18 W / cm ( 2 ) ( 803 nm, 0. 5 seconds ) without skin surface cooling or at 200 W / cm ( 2 ) ( 809 nm, 0. 5 seconds ) with cooling.
The outcome of this Research: The observations during 1 - 2 months showed that soft treatment decreased the number of active elements, strapped erythema and inflammation, and considerably improved the skin state adrift any side effects. At high power densities ( up to 200 W / cm ( 2 ) ), ICG stained inflammatory elements were destroyed for light exposures of 0. 5 seconds.
The Report's Conclusions: Based on the concept that hair follicle, especially sebaceous gland, can be intensively and selectively stained by ICG useful to dye diffusion finished pilosebaceous canal and its fast uptake by living microorganisms, by vital keratinocytes of epithelium of the canal and sebaceous duct, and by rapidly proliferating sebocytes, new technologies of soft and thermal lesions treatment that could be used in clinical treatment of were proposed.
Report Title: A pilot study of ICG laser therapy of vulgaris: photodynamic and photothermolysis treatment.
Researcher ( s ): Tuchin VV, Genina EA, Bashkatov AN, Simonenko GV, Odoevskaya OD, Altshuler GB
From Chronicle: Lasers Surg Med, 33 ( 5 ): 296 - 310 2003
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Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the sphere & translated into 27 languages. He has a special interest in skin chagrin.
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