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Skin disease, common in adolescence, causing inflammation of the sebaceous glands and characterised by closed and/or open comedones, papules and/or pustules on the face, neck and upper body.

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Treatment Of Moderate To Severe Inflammatory Acne Vulgaris - Light Treatment
By A J Jackson

Summary of research:

The use of photodynamic therapy ( PDT ) with 20 % 5 - aminolevulinic acid ( ALA ) for the treatment of vulgaris has been explored. This study evaluates the safety and efficacy of a new Advanced Fluorescence Technology ( AFT ) pulsed light source ( 420 - 950 nm ) for photoactivation in ALA PDT for the treatment of moderate to severe inflammatory facial vulgaris. Nineteen subjects received 4 ALA PDT treatments with the AFT pulsed light source. Treatments were spaced 2 weeks apart. ALA was incubated for 15 to 30 minutes. At the end of the fourth treatment, the total reductions in inflammatory and noninflammatory

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lesion counts were 54. 5 % and 37. 5 %, respectively. Median Global Severity Scores suggest a trend toward reduction after several treatments. Investigator and subject assessments show moderate to marked improvement in most patients. The new AFT pulsed light source with ALA PDT appears to be a safe and effective modality for the treatment of moderate to severe inflammatory vulgaris.

Report Title: Treatment of moderate to severe inflammatory vulgaris: photodynamic therapy with 5 - aminolevulinic acid and a novel advanced fluorescence technology pulsed light source.
Researcher ( s ): Gold MH, Biron JA, Boring M, Bridges TM, Bradshaw VL
From Journal: J Drugs Dermatol, 6 ( 3 ): 319 - 22 2007

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

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	Photodynamic Therapy For The Treatment Of Acne By A J Jackson Summary of research: Photodynamic therapy ( PDT ) with use of topical 5 - aminolevulinic acid ( ALA, Levulan Kerastick, Dusa Pharmaceuticals, Inc., Wilmington, MA ) Read more...
	Intense Continuous Light Therapy For Acne By A J Jackson Summary of research: Topical antibiotics, isotretinoin or systemic antibiotics are usually used for Acne therapy. However, isotretinoin cannot produce used during pregnancy Read more...

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