Acne antibiotics - Acne Treatments

Anxiety And Depressive Scores In Acne Patients Treated With Isotretinoin
By A J Jackson


Summary of research:

Isotretinoin therapy and its alleged counteractive psychiatric effects have received burly media attention during the past years. The account of this pilot study was to investigate whether there was any faction between isotretinoin therapy and anxiety, depression or suicidal ideation.

The researchers methods: Forty - five patients with severe recalcitrant were enrolled in this study. Isotretinoin was administered at a dose of 0. 5 - 1 mg / kg per day in two divided doses with food for 16 weeks. All patients received a complete dermatological examination and the severity levels of their were scored according to the Leeds Revised Evaluating mode at baseline ( before isotretinoin treatment ) and pursue - up assessments at weeks 4, 8 and 16 of the treatment. Severity

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of responsibility and depressive symptoms were assessed with the Clinical Grievance Scale and Montgomery - Asberg Depression Evaluating Scale before and upon completion of the 16 - week isotretinoin treatment.

The outcome of this Inquire into: Twenty - three patients over the final assessment. There was a statistically significant decrease in hindrance scores. Depression scores also decreased but were not statistically momentous. No responsive committed or attempted suicide.

The Report's Conclusions: This pilot study was unable to detect an association between the use of isotretinoin and an increased risk for anxiety, depression, or suicidal thoughts.

Report Title: A co-pilot study evaluating anxiety and depressive scores in patients treated with isotretinoin.
Researcher ( s ): Ferahbas A, Turan MT, Esel E, Utas S, Kutlugun C, Kilic CG
From Journal: J Dermatolog Treat, 15 ( 3 ): 153 - 7 2004

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Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin disquiet.

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