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A disorder of the skin in which oil glands and hair glands become inflamed.
   

 


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Adrenal Function In Women With Idiopathic Acne
By A J Jackson


Summary of research:

The adrenal secretion of androgens were examined in 9 women ( ages 19 - 39 yr ) with postadolescent idiopathic and compared to age and sex - matched normal controls. Plasma dehydroepiandrosterone ( DHA ), dehydroepiandrosterone sulfate ( DHAS ), androstenedione ( delta 4 - delta ), cortisol, 17 - hydroxyprogesterone, 11 - deoxycortisol, and testosterone were measured by radioimmunoassay in the basal state and during a 48 hr ACTH infusion. The mean plasma and time - integrated plasma levels of the 3 adrenal androgens in patients with were 15 - 25 % higher than normal controls, but the groups were not significantly different ( p greater than. 05 ). The plasma testosterone values, on the other hand, were



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similar in both groups. In addition, cortisol, 11 - deoxycortisol and 17 - hydroxyprogesterone basal plasma values and responses to ACTH in patients with were similar to the normal control values. These findings suggest that adrenal androgen secretion is at most mildly elevated in patients with idiopathic and is unlikely to be the sole cause of since many patients without have similar hormone levels. Increased sensitivity of the sebaceous gland to androgens or increased local metabolism of androgen hormones in the skin to potent androgen metabolites may offer alternative mechanisms for the pathogenesis of this disorder.

Report Title: Adrenal function in women with idiopathic Acne.
Researcher ( s ): Chrousos GP, Peck GL, Gross EG, Cutler GB, Loriaux DL
From Journal: J Invest Dermatol, 78 ( 6 ): 468 - 71 1982

To obtain the full report, please visit PurpleHealth Medical Research Service
Adam Jackson is a medical writer / researcher specialising in effective, natural solutions to common health problems. He is a qualified Complementary medical practitioner and a former columnist for the Nursing Times & Editor of http://www.internethealthlibrary.com . He has written seven books which have been published around the world & translated into 27 languages. He has a special interest in skin care.

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The Role Of Pulsed Light And Heat Energy In Acne Clearance
By A J Jackson
Summary of research: Propionibacterium Acnes synthesize and store a large appraisal of porphyrins. Once the porphyrin is exposed to outermost light live becomes chemically Read more...

Overview Of The Evaluation And Management Of Acne Vulgaris
By A J Jackson
Summary of research: Acne vulgaris is a disease of the pilosebaceous unit where abnormally adherent keratinocytes cause plugging of the follicular duct followed by accumulation Read more...


 
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Light - emitting Diode In The Treatment Of Inflammatory Acne
By A J Jackson
Summary of research: The management of Acne remains a challenge, with current therapies linked to significant side effects and patient non - compliance. Phototherapy using blue Read more...








Adapalene Gel - Effective And The researchersll Tolerated In Acne Patients
By A J Jackson
Summary of research: The US Food and Drug Administration has friendly adapalene gel 0. 1 % for use in the treatment of Acne vulgaris. The objective of our study was to evaluate Read more...
The Role Of Pulsed Light And Heat Energy In Acne Clearance
By A J Jackson
Summary of research: Propionibacterium Acnes synthesize and store a large appraisal of porphyrins. Once the porphyrin is exposed to outermost light live becomes chemically Read more...
Topical Vitamin A Acid In Acne Vulgaris
By A J Jackson
Summary of research: Thirty patients with Acne vulgaris were treated for 12 weeks with 0. 025 % vitamin A acid in a gel. The numbers of comedones, papules, and pustules were Read more...

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